Ifng interferon gamma [Mus musculus (house mouse)] - Gene - NCBI
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Ifngprovided by
interferon gammaprovided by
Primary source
See related
protein coding
RefSeq status
E M C C V E M E E G R M M M M M Mus
Also known as
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Expression
Low expression observed in reference dataset
See Ifng in
Annotation release
GRCm38.p4 ()
Build 37.2
previous assembly
MGSCv37 ()
Chromosome 10 - NC_
Genomic Sequence:
NC_ Chromosome 10 Reference GRCm38.p4 C57BL/6J
NC_ Chromosome 10 Reference MGSCv37 C57BL/6J
Go to nucleotide:
Related articles in PubMed
GeneRIFs: Gene References Into Functions
Title: Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5.
Title: The inflammatory cytokine interferon-gamma inhibits sortilin-1 expression in hepatocytes via the JAK/STAT pathway.
Title: IFN-γ induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense.
Title: The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis.
Title: Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments.
Title: TIM-4 Identifies IFN-γ-Expressing Proinflammatory B Effector 1 Cells That Promote Tumor and Allograft Rejection.
Title: Innate IFN-γ-Producing Cells Developing in the Absence of IL-2 Receptor Common γ-Chain.
Title: IFN-γ-Expressing Th17 Cells Are Required for Development of Severe Ocular Surface Autoimmunity.
Title: Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks.
Title: Catch and Release of Cytokines Mediated by Tumor Phosphatidylserine Converts Transient Exposure into Long-Lived Inflammation.
Ifng (e-PCR), detects polymorphism
K00083 (e-PCR)
PMC (e-PCR)
Ifng (e-PCR), detects polymorphism
Il12b (e-PCR), detects polymorphism
PMC (e-PCR)
NoName (e-PCR)
PMC (e-PCR)
Ifng (e-PCR), detects polymorphism
Ifng (e-PCR), detects polymorphism
PMC (e-PCR)
PMC (e-PCR)
PMC (e-PCR)
PMC (e-PCR)
PMC (e-PCR)
PMC (e-PCR)
PMC (e-PCR)
PMC (e-PCR)
PMC (e-PCR)
Ifng (e-PCR), detects polymorphism
PMC (e-PCR)
D10Mit24 (e-PCR), detects polymorphism
PMC (e-PCR)
PMC97984P1 (e-PCR)
Inferred from Electronic Annotation
Inferred from Physical Interaction
Evidence Code
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Mutant Phenotype
Inferred from Direct Assay
Inferred from Genetic Interaction
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Electronic Annotation
Inferred from Mutant Phenotype
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Mutant Phenotype
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Mutant Phenotype
Inferred from Direct Assay
Inferred from Mutant Phenotype
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Mutant Phenotype
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Mutant Phenotype
Inferred from Direct Assay
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Mutant Phenotype
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Genetic Interaction
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Electronic Annotation
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Evidence Code
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Direct Assay
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Inferred from Sequence Orthology
Preferred Names
interferon gamma
gamma interferon
These reference sequences exist independently of genome builds.
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in
mRNA and Protein(s)
interferon gamma precursor
Status: REVIEWED
Source sequence(s)
Consensus CDS
UniProtKB/Swiss-Prot
Conserved Domains (1)
Location:14 → 150
IFN- Interferon gamma
The following sections contain reference sequences that belong to a
specific genome build.
Reference GRCm38.p4 C57BL/6J
NC_ Reference GRCm38.p4 C57BL/6J
Protein Accession
GenPept Link
UniProtKB Link
The following
resources are supplied by external providers. These providers are responsible for maintaining the links.
Interologous Interaction Database
Allen Brain Atlas
CREB Target Gene Database
Eukaryotic Promoter Database
GenScript latest version of gene cDNA ORF Clone
GeneNetwork
Genevisible
Genitourinary Development Molecular Anatomy Project
Immunological Genome Project
Ingenuity Pathways Analysis
KOMP Repository
Kyoto Encyclopedia of Genes and Genomes
NIA Mouse Gene Index
Nuclear Receptor Signaling Atlas (NURSA)
OrthoDB: The Hierarchical Catalog of Orthologs
PANTHER Classification System
PhosphoSitePlus
Protein Ontology Consortium
SeekQuence Research Antibodies
iHOP - Information Hyperlinked over Proteins
iRefWeb - iRefIndex release 9.0 - Consolidated Interactome
Addgene Non-profit plasmid repository
Creative Biomart
ExactAntigen/Labome
GeneCopoeia Inc.
Sino Biological Inc.
antibodies-online
GeneWeaver
InterologFinder.org
Supplemental Content
Order cDNA clone
BioAssays related to the gene by protein target or RNAi target
Summarized PubChem Data on the gene, showing the active data by default
PubChem BioAssays done on the Gene target
BioAssays that contain the gene as the target of a RNAi reagent
BioProjects related to a gene
BioSystems
Link to CCDS
Related CDD
Full text in PubMedCentral identified from shared sequence links
Overlapping genes and two nearest non-overlapping genes on either side
Related Genome
Related GEO
Related HomoloGene
Link to related mapview entry
Link to related Nucleotide entry
Related Probe entry
Link to related protein entry
PubChem Compounds
PubChem Substances
Link to related PubMed entry
Link to related PubMed article from GeneRIFs
Citations in PubMed identified from shared sequence and PMC links.
Link to Protein RefSeqs
Link to Nucleotide RefSeq RNAs
Related SNP records
SNPs linked from GeneView
Link to related taxonomy entry
Links to unigene
Ifng interferon gamma [Mus musculus]Gene ID:15978
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