Protein knowledgebaseSequence archiveHelp pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects.Sequence clustersProtein sets from fully sequenced genomesAnnotation systemsSystems used to automatically annotate proteins with high accuracy:Supporting dataSelect one of the options below to target your search:You are using a version of browser that may not display all the features of this website. Please consider upgrading .
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RNA-binding protein 28Rbm28Mus musculus (Mouse)-Annotation score: -Experimental evidence at protein leveliFunctioniNucleolar component of the spliceosomal ribonucleoprotein complexes.GO - Molecular functioniGO - Biological processiKeywordsiMolecular functionBiological process, Names & TaxonomyiProtein namesiRecommended name:RNA-binding protein 28Alternative name(s):RNA-binding motif protein 28Gene namesiName:OrganismiTaxonomic identifieri
[]Taxonomic lineagei >
Proteomesi Componenti: Chromosome 6 Organism-specific databasesMGIi Rbm28Subcellular locationi
Extracellular region or secreted
Plasma membrane
Cytoskeleton
Peroxisome
Golgi apparatus
Mitochondrion
Manual annotation
Automatic computational assertionGraphics by Christian S Source: Keywords - Cellular componenti, PTM / ProcessingiMolecule processingFeature keyPosition(s)DescriptionActionsGraphical viewLengthInitiator methionineiRemovedManual assertion inferred from sequence similarity toiChainiPRO_RNA-binding protein 28 749Amino acid modificationsFeature keyPosition(s)DescriptionActionsGraphical viewLengthModified residueiN-acetylalanineManual assertion inferred from sequence similarity toi1Modified residueiPhosphoserineManual assertion inferred from sequence similarity toi1Modified residueiPhosphoserineManual assertion inferred from combination of experimental and computational evidencei"A tissue-specific atlas of mouse protein phosphorylation and expression.", , , , , , , , ,
[] [] []Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-231 AND SER-239, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].1Modified residueiPhosphoserineManual assertion inferred from combination of experimental and computational evidencei"A tissue-specific atlas of mouse protein phosphorylation and expression.", , , , , , , , ,
[] [] []Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-231 AND SER-239, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].1Modified residueiPhosphoserineManual assertion inferred from sequence similarity toi1Cross-linkiGlycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Manual assertion inferred from sequence similarity toiKeywords - PTMi, , , Proteomic databasesEPDiMaxQBiPaxDbiPeptideAtlasiPRIDEiPTM databasesiPTMnetiPhosphoSitePlusiSwissPalmiExpressioniGene expression databasesBgeeiCleanExiExpressionAtlasi baseline and differentialGenevisiblei MMInteractioniSubunit structureiInteracts with U1, U2, U4, U5, and U6 spliceosomal small nuclear RNAs (snRNAs).Protein-protein interaction databasesBioGridi, 3 interactorsDIPiIntActi, 1 interactorSTRINGiStructureiSecondary structure1750Legend: HelixTurnBeta strandPDB Structure known for this areaFeature keyPosition(s)DescriptionActionsGraphical viewLengthBeta strandiManual assertion inferred from combination of experimental and computational evidencei5HelixiManual assertion inferred from combination of experimental and computational evidencei9Beta strandiManual assertion inferred from combination of experimental and computational evidencei5Beta strandiManual assertion inferred from combination of experimental and computational evidencei3Beta strandiManual assertion inferred from combination of experimental and computational evidencei9HelixiManual assertion inferred from combination of experimental and computational evidencei11TurniManual assertion inferred from combination of experimental and computational evidencei5Beta strandiManual assertion inferred from combination of experimental and computational evidencei5Beta strandiManual assertion inferred from combination of experimental and computational evidencei53D structure databasesSelect the link destinations:PDBeiRCSB PDBiPDBjiPDB entryMethodResolution (?)ChainPositionsPDBsumNMR-A[]ProteinModelPortaliSMRiModBaseiMobiDBiMiscellaneous databasesEvolutionaryTraceiFamily & DomainsiDomains and RepeatsFeature keyPosition(s)DescriptionActionsGraphical viewLengthDomainiRRM 1Manual assertion according to rulesi 77DomainiRRM 2Manual assertion according to rulesi 78DomainiRRM 3Manual assertion according to rulesi 85DomainiRRM 4Manual assertion according to rulesi 106Compositional biasFeature keyPosition(s)DescriptionActionsGraphical viewLengthCompositional biasiAsp/Glu-rich (acidic) 82Keywords - DomainiPhylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOVERGENiInParanoidiKOiOMAiOrthoDBiTreeFamiFamily and domain databasesGene3Di, 4 hitsInterProi Nucleotide-bd_a/b_plait_sf RBD_domain_sf RRM_domPfami RRM_1, 4 hitsSMARTi RRM, 4 hitsSUPFAMi SSF54928, 4 hitsPROSITEi RRM, 4 hitsSequenceiSequence statusi: Complete.Sequence processingi: The displayed sequence is further processed into a mature form.Q8CGC6-1 []
50MAGLTLFVGR LPPSARSDQL EELFSQVGPV KQCFVVTEKG SKACRGFGYV
100TFSMLEDVQR ALKEITTFEG CKIDVTVAKK KLRNKSKETR KNENAESPKK
150EPKHKKAKVA DKKARLIIRN LSFKCSEDDL KAVFTHYGTV LEVNIPKKPD
200GKMRGFAFVQ FKNLLEAGKA LKGANMKEIK GRTVAVDWAV AKDKYKDAQH
250ASAPGVKKSS DRKPKESGKK NCRVEEQVED SDDEEDDDSH DDEEERESTI
300ASPVSVHKRA VKRAAPEESI EEDDSYEDSD LEEGGSSYDE GTVDSESSAE
350DQEDEDVPVS EKKKRKLPSD VTEGKTVFIR NLSFDSEEEA LGEVLQQFGD
400LKYVRVVLHP DTEHSKGCAF AQFMTQEAAQ KCLAAASLEA EGGGLKLDGR
450QLKVDLAVTR DEAAKLQTKK VKKPTGTRNL YLAREGLIRA GTKAAEGVSA
500ADMAKRERFE LLKHQKLKNQ NIFVSQTRLC LHNLPKAVDD KQLRKLLLEA
550TRGEKGVRIK ECRVMRDLKG VHGKMKGQSL GYAFAEFQKH EHALRALRHF
600NNNPEIFGSQ KRPIVEFSLE DRRKLKVKEL RIQRSLQKME SKPVTSKPQK
650EQKEVGKDKQ QKVVQSATQD QSKAPGEQKG KAGSTSWSGF QTKAEVEQVE
700LPDGKKRRKV LALPSHRGPK IRLRDKGKVK SLPSRKPKPQ MGQRKQKKQQ
750LASSVQAPKR KAKENKAEAR FNQLVEQYKQ KLLGPSKGAP LMKRSKWFDS 75084,214July 27, 2011 - v4Checksum:iC767D7CBLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutterExperimental InfoFeature keyPosition(s)DescriptionActionsGraphical viewLengthSequence conflictiS → I in
(PubMed:).1Sequence conflictiDE → GR in
(PubMed:).2Sequence conflictiL → P in
(PubMed:).1Sequence conflictiL → F in
(PubMed:).1Sequence conflictiV → A in
(PubMed:).1Sequence conflictiV → A in
(PubMed:).1Sequence conflictiV → A in
(PubMed:).1Sequence conflictiS → T in
(PubMed:).1Sequence conflictiS → T in
(PubMed:).1Sequence databasesSelect the link destinations:EMBLiGenBankiDDBJi mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
Genomic DNA No translation available. mRNA Translation:
mRNA Translation: CCDSiRefSeqi, UniGeneiGenome annotation databasesEnsembli; ; GeneIDiKEGGiUCSCi mouseSimilar proteinsi753753752753753752756765 mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
Genomic DNA No translation available. mRNA Translation:
mRNA Translation: CCDSiRefSeqi, UniGenei3D structure databasesSelect the link destinations:PDBeiRCSB PDBiPDBjiPDB entryMethodResolution (?)ChainPositionsPDBsumNMR-A[]ProteinModelPortaliSMRiModBaseiMobiDBiProtein-protein interaction databasesBioGridi, 3 interactorsDIPiIntActi, 1 interactorSTRINGiPTM databasesiPTMnetiPhosphoSitePlusiSwissPalmiProteomic databasesEPDiMaxQBiPaxDbiPeptideAtlasiPRIDEiProtocols and materials databasesStructural Biology KnowledgebaseGenome annotation databasesEnsembli; ; GeneIDiKEGGiUCSCi mouseOrganism-specific databasesCTDiMGIi Rbm28Phylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOVERGENiInParanoidiKOiOMAiOrthoDBiTreeFamiMiscellaneous databasesChiTaRSi mouseEvolutionaryTraceiPROiSOURCEiGene expression databasesBgeeiCleanExiExpressionAtlasi baseline and differentialGenevisiblei MMFamily and domain databasesGene3Di, 4 hitsInterProi Nucleotide-bd_a/b_plait_sf RBD_domain_sf RRM_domPfami RRM_1, 4 hitsSMARTi RRM, 4 hitsSUPFAMi SSF54928, 4 hitsPROSITEi RRM, 4 hitsProtoNeti Q9CSE6Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004Last sequence update: July 27, 2011Last modified: May 23, 2018This is version 127 of the entry and version 4 of the sequence. Entry statusiReviewed (UniProtKB/Swiss-Prot)Annotation programMiscellaneousiKeywords - Technical termi, , We'd like to inform you that we have updated our
with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.Protein knowledgebaseSequence archiveHelp pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects.Sequence clustersProtein sets from fully sequenced genomesAnnotation systemsSystems used to automatically annotate proteins with high accuracy:Supporting dataSelect one of the options below to target your search:You are using a version of browser that may not display all the features of this website. Please consider upgrading .
From June 20, 2018 all traffic will be automatically redirected to HTTPS.
Cytidine and dCMP deaminase domain-containing protein 1Cdadc1Mus musculus (Mouse)-Annotation score: -Experimental evidence at transcript leveliFunctioniMay play an important role in testicular development and spermatogenesis.CofactoriSitesFeature keyPosition(s)DescriptionActionsGraphical viewLengthMetal bindingiZ catalytic1Active siteiProton donor1Metal bindingiZ catalytic1Metal bindingiZ catalytic1GO - Molecular functioniGO - Biological processiKeywordsiMolecular functionLigand, Names & TaxonomyiProtein namesiRecommended name:Cytidine and dCMP deaminase domain-containing protein 1Gene namesiName:OrganismiTaxonomic identifieri
[]Taxonomic lineagei >
Proteomesi Componenti: Chromosome 14 Organism-specific databasesMGIi Cdadc1Subcellular locationi
Extracellular region or secreted
Plasma membrane
Cytoskeleton
Peroxisome
Golgi apparatus
Mitochondrion
Manual annotation
Automatic computational assertionGraphics by Christian S Source: PTM / ProcessingiMolecule processingFeature keyPosition(s)DescriptionActionsGraphical viewLengthChainiPRO_Cytidine and dCMP deaminase domain-containing protein 1 523Proteomic databasesPaxDbiPRIDEiPTM databasesiPTMnetiPhosphoSitePlusiExpressioniGene expression databasesBgeeiCleanExiExpressionAtlasi baseline and differentialGenevisiblei MMInteractioniGO - Molecular functioniProtein-protein interaction databasesSTRINGiStructurei3D structure databasesProteinModelPortaliSMRiModBaseiMobiDBiFamily & DomainsiDomains and RepeatsFeature keyPosition(s)DescriptionActionsGraphical viewLengthDomainiCMP/dCMP-type deaminase 1Manual assertion according to rulesi 99DomainiCMP/dCMP-type deaminase 2Manual assertion according to rulesi 166Sequence similaritiesiBelongs to the .Phylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOVERGENiInParanoidiPhylomeDBiFamily and domain databasesCDDi deoxycytidylate_deaminase, 1 hitInterProi APOBEC/CMP_deaminase_Zn-bd CMP_dCMP_dom Cytidine_deaminase-like dCMP_deaminase-rel Deoxycytidylate_deaminase_domPANTHERi PTHR11086, 1 hitPfami dCMP_cyt_deam_1, 2 hitsSUPFAMi SSF53927, 2 hitsPROSITEi CYT_DCMP_DEAMINASES_1, 1 hit CYT_DCMP_DEAMINASES_2, 2 hitsSequences (5)iSequence statusi: Complete.This entry describes 5 isoformsi produced by alternative splicing.
(identifier: Q8BMD5-1)
[]This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
50MKETDQMQSL EGSGAERSVG TQTGSMTGQI PRLSKVNLFT LLSLWMELFP
100GVEAQGQKSQ KTEEESRGPL GDNEELTRVS TEKKQVKKTG LVVVKNMKII
150GLHCSSEDLH TGQIALIKHG SRLKNCDLYF SRKPCSACLK MIVNAGVNRI
200SYWPSDPEIS LLTEASSSED AKLDAKAAER LKSNSRAHVC VLLQPLVCYM
250VQFVEETSYK CDFIQKTAKA LPGADTDFYS ECKQERIKEY EMLFLVSNEE
300RHKQILMTIG LESLCEDPYF SNLRQNMKDL ILLLATVASS VPNLKHFGFY
350CSSPEQINEI HNQSLPQEVA RHCMVQARLL AYRTEDHKTG VGAVIWAEAK
400SRSCDGTGAM YFIGCGYNAF PVGSEYADFP HMDDKHKDRE IRKFRYIIHA
450EQNALTFRCQ DIKPEERSMI FVTKCPCDEC VPLIKGAGIK QIYAGDVDVG
500KKKADISYMK FGELEGVRKF TWQLNPSEAY SLDPNEPERR ENGVLRRRSA
520 KDEQRSSKRP RLETRSAGRA TLQ
52359,062March 1, 2003 - v1Checksum:i49EB274BLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutter (identifier: Q8BMD5-2)
[]The sequence of this isoform differs from the canonical sequence as follows:
: NGVLRRRS → RSATTACF
: Missing.49956,237Checksum:iE0DC7ABLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutter (identifier: Q8BMD5-3)
[]The sequence of this isoform differs from the canonical sequence as follows:
: NGVLRR → SFFFMP
: Missing.49756,156Checksum:iFDC6D13F200B5C62BLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutter (identifier: Q8BMD5-4)
[]The sequence of this isoform differs from the canonical sequence as follows:
: NGVLRRRSA → KHLSIKRSH
: Missing.50056,487Checksum:i46A1BDEBLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutter (identifier: Q8BMD5-6)
[]The sequence of this isoform differs from the canonical sequence as follows:
: Missing.
: Missing.38343,376Checksum:iA65BC08BLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutterSequence cautioniThe sequence
differs from that shown. Reason: Frameshift at position .Experimental InfoFeature keyPosition(s)DescriptionActionsGraphical viewLengthSequence conflictiH → R in
(PubMed:).1Sequence conflictiIHN → VHS in
(PubMed:).3Sequence conflictiR → H in
(PubMed:).1Sequence conflictiR → H in
(PubMed:).1Alternative sequenceFeature keyPosition(s)DescriptionActionsGraphical viewLengthAlternative sequenceiVSP_027817Missing
in isoform . Manual assertion based on opinion ini"The transcriptional landscape of the mammalian genome.", , , , , , , , , , , , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 6). 96Alternative sequenceiVSP_027818Missing
in isoform . Manual assertion based on opinion ini"The transcriptional landscape of the mammalian genome.", , , , , , , , , , , , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 6). 44Alternative sequenceiVSP_027819NGVLRRRSA → KHLSIKRSH in isoform . Manual assertion based on opinion ini"The transcriptional landscape of the mammalian genome.", , , , , , , , , , , , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 6)."The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF
(ISOFORM 4).9Alternative sequenceiVSP_027820NGVLRRRS → RSATTACF in isoform . Manual assertion based on opinion ini"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF
(ISOFORM 4).8Alternative sequenceiVSP_027821NGVLRR → SFFFMP in isoform . Manual assertion based on opinion ini"The transcriptional landscape of the mammalian genome.", , , , , , , , , , , , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 6).6Alternative sequenceiVSP_027822Missing
in isoform . Manual assertion based on opinion ini"The transcriptional landscape of the mammalian genome.", , , , , , , , , , , , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 6). 26Alternative sequenceiVSP_027823Missing
in isoform . Manual assertion based on opinion ini"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF
(ISOFORM 4). 24Alternative sequenceiVSP_027824Missing
in isoform . Manual assertion based on opinion ini"The transcriptional landscape of the mammalian genome.", , , , , , , , , , , , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 6)."The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[] [] []Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF
(ISOFORM 4). 23Sequence databasesSelect the link destinations:EMBLiGenBankiDDBJi mRNA Translation:
Frameshift. mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation: CCDSi [] [] []RefSeqi, ,
[], UniGeneiGenome annotation databasesEnsembli; ;
[]GeneIDiKEGGiUCSCi mouse [] mouse [] mouse [] mouse []Keywords - Coding sequence diversityiSimilar proteinsi565525120523523514514581516516 mRNA Translation:
Frameshift. mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation:
mRNA Translation: CCDSi [] [] []RefSeqi, ,
[], UniGenei3D structure databasesProteinModelPortaliSMRiModBaseiMobiDBiProtein-protein interaction databasesSTRINGiPTM databasesiPTMnetiPhosphoSitePlusiProteomic databasesPaxDbiPRIDEiProtocols and materials databasesStructural Biology KnowledgebaseGenome annotation databasesEnsembli; ;
[]GeneIDiKEGGiUCSCi mouse [] mouse [] mouse [] mouse []Organism-specific databasesCTDiMGIi Cdadc1Phylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOVERGENiInParanoidiPhylomeDBiMiscellaneous databasesChiTaRSi mousePROiSOURCEiGene expression databasesBgeeiCleanExiExpressionAtlasi baseline and differentialGenevisiblei MMFamily and domain databasesCDDi deoxycytidylate_deaminase, 1 hitInterProi APOBEC/CMP_deaminase_Zn-bd CMP_dCMP_dom Cytidine_deaminase-like dCMP_deaminase-rel Deoxycytidylate_deaminase_domPANTHERi PTHR11086, 1 hitPfami dCMP_cyt_deam_1, 2 hitsSUPFAMi SSF53927, 2 hitsPROSITEi CYT_DCMP_DEAMINASES_1, 1 hit CYT_DCMP_DEAMINASES_2, 2 hitsProtoNeti Q9D7F3Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007Last sequence update: March 1, 2003Last modified: February 28, 2018This is version 108 of the entry and version 1 of the sequence. Entry statusiReviewed (UniProtKB/Swiss-Prot)Annotation programMiscellaneousiKeywords - Technical termi, DocumentsMouse Genome Database (MGD) cross-references in UniProtKB/Swiss-ProtIndex of protein domains and familiesWe'd like to inform you that we have updated our
with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.Protein knowledgebaseSequence archiveHelp pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects.Sequence clustersProtein sets from fully sequenced genomesAnnotation systemsSystems used to automatically annotate proteins with high accuracy:Supporting dataSelect one of the options below to target your search:You are using a version of browser that may not display all the features of this website. Please consider upgrading .
From June 20, 2018 all traffic will be automatically redirected to HTTPS.
Collagen triple helix repeat-containing protein 1Cthrc1Rattus norvegicus (Rat)-Annotation score: -Experimental evidence at protein leveliFunctioniIts overexpression in smooth muscle cell lines increases their migratory ability and inhibits collagen type I expression. May act as a negative regulator of collagen matrix deposition.GO - Molecular functioniGO - Biological processiInferred from mutant phenotypeiNames & TaxonomyiProtein namesiRecommended name:Collagen triple helix repeat-containing protein 1Gene namesiName:OrganismiTaxonomic identifieri
[]Taxonomic lineagei >
Proteomesi Componenti: Chromosome 7 Organism-specific databasesRGDi Cthrc1Subcellular locationi
Extracellular region or secreted
Plasma membrane
Cytoskeleton
Peroxisome
Golgi apparatus
Mitochondrion
Manual annotation
Automatic computational assertionGraphics by Christian S Source: "Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.", , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [MRNA], POSSIBLE FUNCTION, GLYCOSYLATION, INDUCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.Keywords - Cellular componenti, PTM / ProcessingiMolecule processingFeature keyPosition(s)DescriptionActionsGraphical viewLengthSignal peptidei 32ChainiPRO_Collagen triple helix repeat-containing protein 1 213Amino acid modificationsFeature keyPosition(s)DescriptionActionsGraphical viewLengthGlycosylationiN-linked (GlcNAc...) asparagine1Post-translational modificationiN-glycosylated.Manual assertion based on experiment ini"Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.", , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [MRNA], POSSIBLE FUNCTION, GLYCOSYLATION, INDUCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.Keywords - PTMiProteomic databasesPaxDbiPRIDEiExpressioniTissue specificityiExpressed after injury in the carotid arteries (at protein level). Expressed in brain, lung, and after injury in fibroblasts of the adventitia and the neointima of the arteries.Manual assertion based on experiment ini"Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.", , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [MRNA], POSSIBLE FUNCTION, GLYCOSYLATION, INDUCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.InductioniStrongly induced in carotid arteries after injury (balloon catheter injury model). By various growth factor (BMP4, TGFB1) in NIH 3T3 cell line.Manual assertion based on experiment ini"Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration.", , , , , , ,
[] [] []Cited for: NUCLEOTIDE SEQUENCE [MRNA], POSSIBLE FUNCTION, GLYCOSYLATION, INDUCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.Gene expression databasesBgeeiGenevisiblei RNInteractioniGO - Molecular functioniProtein-protein interaction databasesSTRINGiStructurei3D structure databasesSMRiModBaseiMobiDBiFamily & DomainsiDomains and RepeatsFeature keyPosition(s)DescriptionActionsGraphical viewLengthDomainiCollagen-like 34Keywords - Domaini, Phylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOGENOMiHOVERGENiInParanoidiOMAiOrthoDBiPhylomeDBiTreeFamiSequenceiSequence statusi: Complete.Sequence processingi: The displayed sequence is further processed into a mature form.Q8CG08-1 []
50MHPQGRAASP QLLLGLFLVL LLLLQLSAPS SASENPKVKQ KALIRQREVV
100DLYNGMCLQG PAGVPGRDGS PGANGIPGTP GIPGRDGFKG EKGECLRESF
150EESWTPNYKQ CSWSSLNYGI DLGKIAECTF TKMRSNSALR VLFSGSLRLK
200CRNACCQRWY FTFNGAECSG PLPIEAIIYL DQGSPELNST INIHRTSSVE
240 GLCEGIGAGL VDVAIWVGTC SDYPKGDAST GWNSVSRIII EELPK
24526,424March 1, 2003 - v1Checksum:i2296FD6DCDBA21F2BLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutterSequence databasesSelect the link destinations:EMBLiGenBankiDDBJi mRNA Translation: RefSeqi, UniGeneiGenome annotation databasesEnsembli; ; GeneIDiKEGGiUCSCi ratSimilar proteinsi245286285282246245286285282246 mRNA Translation: RefSeqi, UniGenei3D structure databasesSMRiModBaseiMobiDBiProtein-protein interaction databasesSTRINGiProteomic databasesPaxDbiPRIDEiProtocols and materials databasesStructural Biology KnowledgebaseGenome annotation databasesEnsembli; ; GeneIDiKEGGiUCSCi ratOrganism-specific databasesCTDiRGDi Cthrc1Phylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOGENOMiHOVERGENiInParanoidiOMAiOrthoDBiPhylomeDBiTreeFamiMiscellaneous databasesPROiGene expression databasesBgeeiGenevisiblei RNFamily and domain databasesProtoNetiMiscellaneousiKeywords - Technical termi, We'd like to inform you that we have updated our
with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.